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Boron neutron capture therapy progresses towards clinical cancer treatments – Physics World
LoginThis is registered to make in to the HubPages Service. Knifeless radiosurgery for Northwest England Cancer patients in Northwest England will have access to advanced radiosurgery when the new Christie radiotherapy centre at Salford Royal Hospital opens in summer Siemens mammography software combines multiple imaging types on single workstation The latest version of Syngo Mammo Report, the mammography workstation from Siemens, for the first time combines tomosynthesis, 3D ultrasound and 3D magnetic resonance imaging MRI with 2D mammography.
Dutch research reactor adapted to produce molybdenum for cancer diagnostics The Technical University of Delft is adapting its nuclear research reactor to be used as a back-up facility for the production of the radioactive isotope molybdenum, when supplies run out. Currently impacting the efficiency of nuclear medicine is an ongoing shortage of the radioisotope Molybdenum 99 Mo PSA blood test predicts risk of death from prostate cancer The PSA blood test commonly used to test for prostate cancer can accurately predict the risk that a 60 year old man will die from prostate cancer within the next 25 years.
Natural orifice surgery removes cancerous prostate through penis Urologists at Mayo Clinic in Arizona have developed a new surgical procedure for the treatment of prostate cancer through the urethra, so that there is no incision on the body. MabCure's blood test for ovarian cancer gets positive results Cancer diagnostics developer MabCure, Inc. Prostate cancer seed cells discovered New treatments for prostate cancer could result from the discovery that basal cells found in benign prostate tissue can turn into cancer cells. Common blood protein combined with nanoparticles kills cancer cells A normally benign protein abundant in human blood appears to be able to zero in on and kill certain cancer cells when paired with nanoparticles, without having to also load the particles with chemotherapy drugs.
Larch tree extract used to deliver drugs inside cancer cells A cancer drug to a polymer from the larch tree, researchers at the Technion-Israel Institute of Technology have developed a 'Trojan Horse' molecule that releases cancer-fighting drugs inside cancer cells, protecting healthy tissue.
Clinical Aspects of Neutron Capture Therapy
Videogame processors reduce radiation in image guided radiation therapy A new approach to processing X-ray data could lower by a factor of ten or more the amount of radiation patients receive during cone beam CT scans, report researchers from the University of California, San Diego.
MRI tracking of tumour ablation by carbon nanotubes A new way of monitoring carbon nanotubes as they destroy tumour cells by laser induced heating has been developed by researchers from Wake Forest University Baptist Medical Center. Global network of proton therapy centres for cancer treatment Proton Therapy USA and CareCapital are to form a new company, Proton Therapy Global Management, to develop a global network of proton therapy centres to provide access to this specialized and highly effective cancer treatment.
Genetic mutation in KRAS gene can trigger melanoma A genetic mutation found in some malignant melanomas can initiate development of this most deadly form of skin cancer, according to a study published in the journal Cancer Research. IntrinsiQ launches IntelliScribe eprescribing system for medical oncology IntrinsiQ, provider of IntelliDose, the leading chemotherapy management software, has launched IntelliScribe, the first integrated eprescribing system for medical oncology.
Life Technologies partners with German Cancer Research Centre to create genome sequencing centre Life Technologies Corporation and the Deutsches Krebsforschungszentrum are collaborating to create the National High-Throughput Sequencing Center, the first national sequencing center in Europe dedicated to systems biology. Blood test for detecting cancers five years before visible in diagnostic imaging A ground-breaking diagnostic test that can identify biomarkers in blood for a range of cancers as much as five years earlier than current diagnostic imaging methods will be launched this month.
RMI , specialists in image-guided radiation therapy for cancer treatment. Magnetic fluorescent nanoparticles highlight brain tumours for MRI and surgery Scientists at Ohio State University have combined two types of nanoparticle to create a 'nanocomposite' that is both magnetic and fluorescent. The aim is to highlight tumours in diagnostic imaging and visually during surgery.
Brainlab announces UK symposia on Novalis Tx radiosurgery platform Image-guided technology developer Brainlab is inviting key UK clinicians and healthcare professionals to a series of free clinical symposia on 27 April in Bristol, 28 April in Sheffield and 29 April in London. Combined colon and kidney surgery using single-incision laparoscopy Surgeons at the University of California, San Diego School of Medicine have carried out a single-incision laparoscopy to perform a combined colectomy and kidney-preserving therapy. HD 3D view in robotic surgery for prostate cancer compensates for lack of touch Robotic surgical technology with its three-dimensional, high-definition view gives surgeons the sensation of touch, even as they operate from a remote console.
Outcomes compare favourably with traditional invasive surgery. Better biomarkers needed for liver cancer detection Widely used biomarkers are not optimal in early detection of liver cancer, the third most common cause of cancer-related death worldwide, according to a study published in Gastroenterology.
Drug screening strategy finds two prototype cancer drugs A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways. Residual brain tumour cells need different treatment from main tumour Tumour cells left behind after surgery were found to be substantially different from the cells in the midst of the tumour mass and could explain why radiation or chemotherapy cannot entirely prevent this deadly disease to reoccur.
Wide variations in treatment for breast cancer in Europe, USA and Japan A global study of nearly 10, women with early breast cancer has found wide variations in how they were treated, despite international consensus on best practice, according to the May issue of the British Journal of Surgery. Domainex collaboration with ICR advances breast cancer drug research Scientists have discovered drug-like compounds that inhibit an enzyme from the PARP superfamily, whose expression leads to the survival of breast cancer cells. These will be screened to find potential drug candidates for further development.
Symposium on deuterium depletion: a new concept in anticancer drug development The First International Symposium on Deuterium Depletion will be held on May in Budapest, Hungary to give researchers and medical practitioners a unique opportunity to get acquainted with a novel tool for submolecular medicine. Genetic test for cancer could result in reduced side effects from treatment in children A genetic analysis technique that can identify a less agressive form of a cancer could enable children to be given less intensive treatment than current practice to reduce their risk of damaging side-effects.
Ambicare launches light-emitting plaster for skin cancer treatment Scottish company Ambicare Health has launched the Ambulight PDT, a light-emitting skin plaster for the treatment of non-melanoma skin cancer using 'photodynamic therapy' PDT. Fluorescent nanoparticles highlight cancerous tissue on operating table Cell-penetrating molecules carrying fluorescent and magnetic tags that stick to and light up tumors help surgeons see more of the tumour tissue on the operating table and make it visible to MRI scans. Proton beam imaging for cancer diagnostics moves a step closer Using a proton beam scan to image a patient prior to treatment would give more accurate density maps and the proton beam would stop more precisely on the tumor.
- Boron neutron capture therapy for brain tumors - Yamamoto - Translational Cancer Research.
- Agitprop : the life of an American working-class radical : the autobiography of Eugene V. Dennett.
- The Anti-Proliferative Effect of Boron Neutron Capture Therapy in a Prostate Cancer Xenograft Model.
US HIFU to fund investigation of focal therapy for prostate cancer in UK The study, which will evaluate quality of life outcomes and safety of focal therapy in the treatment of localized prostate cancer will involve four centers initially and may expand to as many as 10 centres in the UK. Mammography gives no added value in breast cancer screening A multicentre study of breast cancer screening has concluded that mammography is unnecessary in women undergoing MRI and current guidelines should be revised to reflect this.
Lilly, Merck, and Pfizer co-operate to accelerate cancer research in Asia The three companies have formed the Asian Cancer Research Group, to accelerate research and ultimately improve treatment for patients affected with the most commonly-diagnosed cancers in Asia. Similar outcomes from open and laparoscopic prostate surgery Researchers at the Memorial Sloan-Kettering Cancer Center, New York compared outcomes in a population based cohort of almost men 66 years of age or older with clinically localized prostate cancer.
Genetic abnormalities predict prostate cancer survival The combination of three genetic abnormalities significantly impacts how long a prostate cancer patient is likely to survive with the disease, according to scientists at the Institute of Cancer Research ICR. Northampton Hospital revamps nuclear medicine department Northampton General Hospital NHS Trust has revamped its Nuclear Medicine department with the installation of state-of-the-art imaging equipment from Siemens Healthcare.
UK Cancer Network implements Varian electronic prescribing and patient record system Chemotherapy software that enables patients to become more involved in managing their own care has been successfully rolled out across The Thames Valley Cancer Network. Antibody-coated nanoparticles in microfluidic chip improve cancer detection fold The Fraunhofer Institute for Silicate Research is developing a highly sensitive method for detecting cancer that can detect single molecules of compounds in the blood that accompany specific types of tumour.
Lung cancer and melanoma genomes decoded Research teams led by the Wellcome Trust Sanger Institute have achieved the first comprehensive analyses of these two cancer genomes.. Colon cancer screening programmes using the Viatronix V3D virtual colonoscopy platform Viatronix has announced that several successful screening programs using the company's virtual colonoscopy technology were highlighted at the 10th International Symposium on Virtual Colonoscopy.
High frequency ultrasound and skin elasticity can identify skin cancer High-frequency ultrasound with elastography can help differentiate between cancerous and benign skin conditions, according to a study presented at the annual meeting of the Radiological Society of North America RSNA.
Materials and Methods
Paxman Coolers launch scalp coolers for reducing hair loss during chemotherapy Huddersfield-based Paxman Coolers are launching their next-generation NPAX1 scalp cooler at Medica in Dusseldorf this week. Scalp coolers provide cancer patients with the best possible chance of retaining their hair whilst undergoing chemotherapy treatment.
Zilico to exhibit pioneering device for rapid detection of cervical cancer at Medica A pioneering device that offers a quicker, more accurate detection of cervical cancer in real time, removing several weeks of waiting for a diagnosis, is being exhibited by British company Zilico Ltd for the first time at Medica Breakthrough in lab-on-chip for fast breast cancer detection The EU-funded MASCOT project has developed a set of modular components for construction of a lab-on-chip system for detection of tumour cells in blood samples.
The modules are now ready for integration into a single lab-on-chip and clinical evaluation. GE Healthcare launches global initiative on 10th anniversary of digital mammography To commemorate the tenth anniversary of digital mammography and its long standing commitment to fighting breast cancer, GE Healthcare has created a digital wall of personal stories from those whose lives have been touched by breast cancer, as well as doctors, scientists and fundraisers who work tirelessly against the disease.
Breast cancer detector with a unique touch Researchers at Drexel University in the US are developing a new portable, low-cost, breast cancer detector based on piezoelectric fingers that measure stiffness and mobility of breast tissue. First evidence of virus in prostate cancer cells A type of virus known to cause leukemia and sarcomas in animals has been found for the first time in malignant human prostate cancer cells.
If it is proven to cause the cancer it would open opportunities for developing diagnostic tests, vaccines, and therapies for treatment. New adaptive cancer therapy system from Siemens The IM-RealART Solution enables treatment plans for radiotherapy to be adapted especially fast to changes in the shape and position of tumours. The treatment plan cn be revised even while the patient is still lying on the treatment table. Bacterial evolution shows how to fine-tune novel anti-cancer drug Biochemists at the Technische Universitaet Muenchen and Nereus Pharmaceuticals have illuminated a reaction pathway that shows how the uncontrolled growth of cancer cells can be thwarted by blocking the action of proteasomes.go to site
Boron neutron capture therapy progresses towards clinical cancer treatments
Turkish Hospital Group orders four RapidArc radiotherapy systems Acibadem Healthcare Group has acquired four additional radiotherapy treatment machines from Varian Medical Systems and expanded its radiotherapy facilities with new centres in Adana and Kayseri. Pioneering cancer treatments developed at Dutch oncology centre with RapidArc radiotherapy Doctors at the VU University Medical Center in Amsterdam have developed new ways to perform radiosurgery on benign acoustic tumours using fast and precise RapidArc radiotherapy technology from Varian Medical Systems. Miniature robot crawls through veins The Technion - Israel Institute of Technology has unveiled a miniature crawling robot ViRob just 1 mm in diameter that has the potential to perform precise medical procedures inside the human body.
Chemical nose could provide more accurate indication of cancer than biomarkers Using a 'chemical nose' array of nanoparticles and polymers, researchers have developed a new, more effective way to differentiate between healthy and cancerous cells and also between metastatic and non-metastatic cancer cells. New discovery shows how cancer spreads A Finnish-led research group has discovered a mechanism that lung cancer cells use when spreading around the body to form metastases.
Focused ultrasound offers better treatment for prostate cancer An experimental treatment that uses ultrasound waves to kill prostate cancer cells may be able to treat men without surgery, with fewer side effects and with only a short stay in hospital, according to a UK study published in the British Journal of Cancer. Radioactive resin microspheres delay progression of colorectal cancer liver metastases The time to progression of disease in patients with colorectal cancer liver metastases who have exhausted all chemotherapy options can be more than doubled through the use of radioactive resin microspheres.
The finding could lead to new ways of treating cancer.
- The Tanner Lectures on Human Values, Volume 10.
- Sustainable Development: Linking Economy, Society, Environment (OECD Insights);
- Symmetry: A Unifying Concept.
- Language Contact, Inherited Similarity and Social Difference: The Story of Linguistic Interaction in the Maya Lowlands?
- Materials and Methods.
- A Dante Of Our Time: Primo Levi and Auschwitz.
- Boron neutron capture therapy in cancer: past, present and future;
The new machines will replace older models and add capacity that will give more patients access to the most advanced cancer care. There is little data from randomized controlled clinical trials to provide any insight into outcomes or survival rates. They provide earlier diagnosis, more accurate tumour location and better assessment of how a patient is responding to cancer treatment. Roche will develop an assay kit using the test on its automated immunoassay analyzers.
It offers a procedural option for patients who are not candidates for surgical resection and have few remaining treatment options. The results are based on patients who began screenings at age 50 and have had consistently negative screenings up to the age of The high growth of this market makes it attractive to companies keen to emulate the blockbuster status achieved by several brands.
However, with several impending patent expiries due, companies will need to work hard to maximize their return throughout the lifecycle of their brands. An article published in the International Journal of Low Radiation claims that short-term low doses of radiation are good for health through boosting the immune system and increasing antibody production.
The author also claims that humans can be deficient in radiation. The study supports the system's clinical flexibility in treating prostate cancer and expands the non-invasive options available to clinicians and patients. The company believes the test will better predict the risk of prostate cancer and help to optimize both screening and treatment. The companies will also explore other areas of collaboration. The report identifies the need to tackle the serious shortage of radiotherapy capacity and radiographers, delays in uptake of new cancer drugs and the need to encourage the spread of improved surgical techniques.
They will be equipped with on-board imager devices for advanced image-guided radiation therapy IGRT treatments. Preliminary results indicate significant reduction in tumour relapse rates. It is being used to support medical specialists in the early diagnosis and prevention of colorectal tumours.